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A Phase III multicenter, randomized, double-blind study was conducted with 223 subjects who were randomized to placebo or mirodenafil at fixed doses of 50 or 100 mg for 12 weeks on an on-demand basis
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[DOI] [PMC free article] [PubMed] [Google Scholar] 248
Once inside the cell, glucocorticoids exert their effects by direct binding to an intracellular receptor, the glucocorticoid receptor (GR) that is a zinc-finger transcription factor belonging to the nuclear hormone receptor superfamily
