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31 P nuclear magnetic resonance study of the brain in Alzheimer's disease J Neuropathol Exp Neurol 1988

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doi: 10.1542/peds.109.4.622 79

The absence of TMA in the urine of germ-free mice without microbiota, 66 the suppression of TMAO production from dietary choline 22 and carnitine 19 in mice treated with broad-spectrum antibiotics, and the re-increase in plasma TMAO levels after antibiotic withdrawal clearly indicate the role of gut microbiota in TMA and TMAO production