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Description
Increased vessel perfusion predicts the efficacy of immune checkpoint blockade

Under this alternative pathway, a medical device that has received FDA marketing authorization (that is, has been approved or cleared by, or had a De Novo classification request granted by, FDA) as a Breakthrough Device, for the indication covered by the Breakthrough Device designation, will need to meet the requirements of 412.87(c)
WeiXDuMLiDWenSXieJLiYet al
Nature 491 , 458462 (2012)

doi: 10.1615/IntJMedMushrooms.v17.i3.20
