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This regulatory stance underscores the need for caution , emphasizing the importance of consulting healthcare professionals and participating in structured clinical trials to ensure safety, efficacy, and compliance with local laws

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Because NRF2 effector functions are contextually integrated in a complex network and because NRF2 activators are able to titrate the overall activity of NRF2, it is plausible that different amounts of NRF2 activity result in qualitatively (rather than just quantitatively) different outputs

J Biol Chem, 1998

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