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Epigenetic deregulation contributes to its pathogenesis by promoting a proinflammatory phenotype in peripheral immune cells

Abstract Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) primarily formed by burning of fossil fuels, wood and other organic materials

10.1073/pnas.1203567109 Proc

This suggests that overexpression of GLT-1 on spinal cord astrocytes attenuates the induction, but not the maintenance, of inflammatory pain and NP

The progeny produced by these methodologies (F1) were mated over two subsequent generations without embryo manipulations and respecting each experimental group (VT, NC), producing F2 and F3 animals (Fig