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122 Furthermore, BM-MSC-EVs carrying miR-34a have been shown to regulate fibroblast function and alleviate RA inflammation by inhibiting cyclin I expression and activating the ATM/ATR/p53 signaling pathway

While iPSCs can mitigate some challenges associated with ESCs, other challenges can be tackled with novel materials and EMFs

In a study testing the immunomodulatory effects of the nonenzymatic antioxidants N-acetylcysteine and cysteamine, significant benefit was observed in glomerulonephritis and mortality in the NZB/W F1 murine model of SLE [134]

The ability of NAC to enhance methylmercury excretion when given orally, its relatively low toxicity, and is wide availability in the clinical setting indicate that it may be an ideal therapeutic agent for use in methylmercury poisoning

The onset of these diseases is often accompanied by abnormalities in mitochondrial energy metabolism, increased oxidative stress, and exacerbated inflammatory responses, further aggravating the pathological processes