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Currently, there is no robust evidence to suggest that GLP-1 receptor agonists directly impair thermoregulation through pharmacological action on temperature control centres in the hypothalamus

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doi: 10.1210/jcem-72-6-1242

Studies in aged animal models have shown that NAD+ precursor supplementation can improve endothelial function as measured by flow-mediated dilation and arterial stiffness parameters in research animals
