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Zhang Z, Liu H, Shi Y, Xu N, Wang Y, Li A

This means: Long-term safety data is evolving Optimal protocols are not established Clinical applications remain experimental Any peptide-related therapy should only be explored under qualified medical supervision

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60,61 CAUSES OF NAD+ DECLINE The above discussion demonstrates clear evidence for the role of NAD+ decline in the development of the hallmarks of aging in the skin, and there has been great interest in understanding the root causes of NAD+ decline to determine strategies to successfully restore cellular NAD+ levels