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Vitamin B12 can reduce abnormal nerve discharge and promote nerve regeneration [26]

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A series of recent studies implicated sirtuins as potent negative regulators of fibroblast activation and myofibroblast differentiation, and sirtuin dysfunction has been linked to the pathogenesis of SSc and other fibro-inflammatory conditions 28,29,38,39,40,41,42

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Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD