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The timing isn't necessarily important, however, I recommend taking it with food to avoid experiencing heartburn and digestive upset

Skip, O.M.D

[PMC free article] [PubMed] [Google Scholar] 140.Silveira J.S., Antunes G.L., Kaiber D.B., da Costa M.S., Marques E.P., Ferreira F.S., Gassen R.B., Breda R.V., Wyse A.T.S., Pitrez P., et al

As a dietary supplement, take 1 mL (26 drops) three (3) times a day in a small amount of water

Thus, it could potentially identify a population susceptible to ischemiareperfusion injury
