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Although side effects are well-tolerated, ME 12 INJECTION 1ML may, in rare cases, cause allergic reactions like itching, rash, or dizziness

The combination of the amylin analogue pramlintide and the recombinant human leptin metreleptin caused significant weight reductions ( - 11.5kg) in comparison with monotherapy in a 24-week phase 2 clinical trial [248]

Open access funding provided by Universit degli Studi di Roma La Sapienza within the CRUI-CARE Agreement Conflict of Interest Giorgio Cruccu received personal fees for advisory boards or consultancy from Angelini, Grunenthal, and Lilly, and personal fees for educational activity by PTS Global Services

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Besides the additional problems of nausea, diarrhea, and high heart rate, another concerning issue with GLP-1 agonists is the loss of muscle mass in those on the drug