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2017;8:e3080

The approximately 6 billion letters (enough to fill 1,000 200-page books) make up the human genome, which contains an estimated 20,000 to 25,000 genes

Autophagy is initiated by the autophagy-activating protein complex that includes the UNC-51-like kinase (ULK1), autophagy-related protein 13L (ATG13L), family interacting protein of 200 kDa (FIP200), and ATG101 [254]

This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol

Products of the pathways are increased