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After desensitization, both patients were reintroduced to intramuscular cyanocobalamin according to individual indications (i.e., Patient 1: 500 g 15/15 days for approximately 8 years

In preclinical research, TB-500 has been examined across multiple tissue systems including skeletal muscle, cardiac tissue, skin, and connective tissue with findings suggesting broad activity in promoting cellular repair, reducing inflammatory markers, and supporting neovascularisation following injury models