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Prospective trials combining ferroptosis inhibitors with neuroprotective agents (such as edaravone) are also needed to explore whether targeting ferroptosis can aid prevention and treatment of PVL in extremely preterm infants

For all three conditions, research has not conclusively shown that SAMe is helpful

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[DOI] [PMC free article] [PubMed] [Google Scholar] 275.Kononov S., Brewer K., Sakai H., Cavalcante F.S., Sabayanagam C.R., Ingenito E.P., Suki B