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Andrographolide modulates OPG/RANKL axis to promote osteoblastic differentiation in MC3T3-E1 cells and protects bone loss during estrogen deficiency in rats

First, although mitochondrial function is related to oxidative stress, inflammation and aging, exactly how mitochondria specifically coordinate with other cellular activities to drive each type of disease still warrants further investigation

Liao, L

doi: 10.1038/s41392-022-01119-3

Osteotropic cancers: From primary tumor to bone
