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Glutathione has been thought to decline as we age, and this deficit is linked to certain health conditions, including cystic fibrosis, diabetes, and Parkinsons
Additionally, proteasomes participate in myriad cellular processes in addition to housekeeping functions such as disposal of damaged proteins
After absorption into enterocytes, soluble curcumin and its metabolites face two potential pathways: efflux back into the intestinal lumen via transporters, such as MRP2, BCRP, and P-gp, or movement into the portal blood through MRP1 and MRP3 transporters (92, 121)
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