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The hyperactivated Nf-kB signal in the CNS induces reactive changes in microglia and astrocytes, further amplifying the neuroinflammatory response [15, 224]
Zu et al., indeed, demonstrated in Drosophila melanogaster that the deletion of miR-14 increased the levels of triacylglycerol and diacylglycerol while its overexpression resulted in the converse effect 94
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[DOI] [PMC free article] [PubMed] [Google Scholar] 76.McNeish AS, Harms HK, Rey J, Shmerling DH, Visakorpi JK, Walker-Smith JA
