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Description
63 Furthermore, BCAT 1 is selectively upregulated in isocitrate dehydrogenase (IDH) wild-type (WT) GBM, and -ketoglutarate (-KG) mediates cell death in BCAT 1-deficient IDH WT GBM
[PubMed] ODell TJ, Christensen BN
These oxidative modifications can induce conformational changes that either promote or inhibit protein activity
Adv Exp Med Biol (2022) 1358:34567
The major limitation associated with all these assays is their lack of specificity
