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Description

Supportive therapy in conditions requiring increased Vitamin C levels (e.g., chronic infections, wound healing)

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141 Additionally, NETs promote tumor growth and metastasis indirectly through mechanisms such as angiogenesis, which is characterized by epithelial-mesenchymal transition (EMT)-related cell migration, degradation of basement membrane proteins mediated by MMPs, and the entrapment of CRC cells

For determining combinatorial treatment effects with either Reversan, MK-571, BSO or Ethacrynic acid, the medium was supplemented with the respective compound 24 h prior to assay preparation to impair transporter/enzyme function before the addition of the second drug