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For instance, gold-based drugs like auranofin show efficacy in treating rheumatoid arthritis and are being studied for their anticancer properties due to their enzyme-inhibitory mechanisms ( auranofin is known to inhibit thioredoxin reductase, an enzyme involved in maintaining cellular redox balance (Tan et al., 2020)

This inherent limitation may have influenced subjective symptom reporting and contributed to variations in OSDI outcomes across studies

Pellegrini JM, Martin C, Morelli MP, Schander JA, Tateosian NL, Amiano NO, Rolandelli A, Palmero DJ, Levi A, Ciallella L, et al