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Experimental studies have investigated its influence on chromatin structure, telomerase-associated activity, and intracellular signalling pathways, with observed effects dependent on concentration, exposure duration, and model system

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Synthetic tetrapeptide (Ala-Glu-Asp-Gly) small, chemically defined, amenable to standard analytical frameworks Studied for hTERT upregulation in human fibroblast cell culture models published in peer-reviewed literature Research tool for telomerase enzyme activity assays, TRAP assays, and telomere length measurement studies Studied in bovine cumulus cell and cumulus-oocyte complex models for telomerase activity published in PMC Examined for DNA binding interactions with specific ATTTG sequence motifs in structural biology research Referenced in over 100 publications primarily from the St

10.1038/s41418-017-0012-4 [DOI] [PMC free article] [PubMed] [Google Scholar] Garzotto D., Giacobini P., Crepaldi T., Fasolo A., De Marchis S