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Comprehensive laboratory monitoring showed no clinically significant changes in vital signs, blood chemistry, or hormonal parameters

Conversion is fine for most healthy younger adults, but can be less efficient in people with MTHFR genetic variants (an estimated 25 to 40% of the population carries at least one variant), people with liver function decline (more common with age), and smokers and former smokers

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Ide H, Fujiya S, Asanuma Y, Tsuji M, Sakai H, Agishi Y

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