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10.1016/j.cmet.2017.07.007 217 KhanS.LuckH.WinerS.WinerD

In this process, carnitine palmitoyltransferase 1 (CPT1), an outer mitochondrial-membrane acyltransferase, is responsible for the conversion of acyl-CoA into acylcarnitine

In other animal studies, butyrate-producing bacteria (F

Several promising compounds have failed in clinical trials due to a range of challenges, including inadequate disease models, late intervention timing, insufficient biomarker validation, and difficulty in distinguishing symptomatic from neuroprotective effects

Excitotoxicity and oxidative stress during inhibition of energy metabolism
