glutathion indicator cellular redox environment dp jones Frontiers Mathematical model for glutathione dynamics
Description
The review concluded that NNMT plays important roles in obesity and type 2 diabetes and validated 5-Amino-1MQ as a potent small-molecule NNMT inhibitor that reverses diet-induced metabolic changes, establishing it as a primary research tool for the NNMT pathway
Hypertension (1999) 33:137984.10.1161/01.HYP.33.6.1379 154 Van BelleEWitzenbichlerBChenDSilverMChangLSchwallRet alPotentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis
GSH regeneration also counteracts the depletion induced by cancer chemotherapeutic agents, potentially leading to development of cancer drug resistance (171)
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