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Areas requiring further investigation include: Tissue-specific dose optimisation: While 10-20 g/kg appears broadly effective across various tissues, whether specific tissues (cartilage versus muscle versus nerve) respond optimally to different doses has not been systematically explored

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Third, 5, 10, and 15 mg are all valid maintenance doses

Step 3 Select your weekly dose TRIUMPH-1 Phase 3 trial doses ranged from 4 mg to 12 mg per week, with all participants beginning at 2 mg before gradual dose escalation every four weeks to improve gastrointestinal tolerability

As noted above, this may be particularly true of the peptides gastroprotective effects [9, 31]