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Although these agents demonstrate well-established efficacy in lowering lipid levels and reducing cardiovascular events, their long-term use is associated with several limitations, including myotoxicity, hepatic dysfunction, poor tolerability, and suboptimal therapeutic responses in certain patient populations (46)

Journal Of Psychiatric Research, 70, 50-57

[DOI] [PubMed] [Google Scholar] 325.Soltani S., Chitsazi M.J., Salehi-Abargouei A

Lithium, tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs), antiepileptics, rifampin, metformin, and amiodarone mainly affect directly thyroid function

Under these conditions, the acetyl-CoA/CoA ratio shows a linear correlation with the acetylcarnitine/carnitine ratio [65,66]