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As a control amino acid of kynurenine metabolism, tryptophan (0.1, 1, and 10), which was neither accumulated in SLE nor influenced by NAC, did not stimulate mTOR activity (data not shown)

doi: 10.1016/S0891-5849(97)00393-6

In Arabidopsis, arGST loss-of-function mutations were additionally linked with an increased content of flavonols 19,45 , most probably due to a second oxidation of accumulating flavan-3,3,4-triol ( 4 ), which is catalysed by At LDOX in vitro 11,12,13