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In contrast, CD8 T cells contribute to neuronal damage by releasing cytotoxic molecules, such as perforin and granzyme, which induce cell death and exacerbate neuroinflammation [157, 158]

Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1 papers.ssrn.com Abstract Circadian clock dysfunction is a common symptom of aging and neurodegenerative diseases, though its impact on brain health is poorly understood