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High levels of Zn, Cd, Cu, Fe, and/or Ni can significantly induce the expression of NA synthase genes (responsible for the synthesis of NA by trimerization of S-adenosylmethionine) (reviewed by Hassan and Aarts, 2011

DEPTOR-Related mTOR Suppression Is Involved in Metformins Anti-Cancer Action in Human Liver Cancer Cells

New evidence suggests that these metabolites are closely associated with ferroptosis in IBD and its pathological processes, indicating that metabolites from gut microbes play a role in controlling IBD onset through the mediation of ferroptosis [11, 12]

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