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doi: 10.1046/j.1365-2125.1998.00803.x

Under normal conditions, Mn and Fe homeostasis are primarily regulated by distinct transporters, but these shared transporters are activated when these ions become imbalanced

This protease was specifically designed to facilitate removal of the protease by allowing simultaneous protease immobilization and cleavage of GST fusion proteins produced from the pGEX-6P vectors pGEX-6P-1, pGEX-6P-2, and pGEX-6P-3

While the results are intriguing, the lack of experimental rigor means we cannot be confident about the specific contribution of BPC-157