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However, as common obesity is a state of leptin resistance, the exogenous administration of even exceedingly high doses of leptin has proven relatively ineffective at reducing body weight [14-16]

Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity

AOD 9604's effects accumulate over weeks

doi: 10.1038/nrd2974

Due to its structure being similar to hGH in some parts, it should not be used for long-term or excessive use without monitoring
