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8a), we implanted fresh primary tumor samples resected from GC patients into immunocompromised mice and then injected PBS or the GCLC inhibitor BSO (i.p

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GSH was calculated as the difference between total glutathione and GSSG and GSH:GSSG ratio was determined

100 U/ml Penicillin-Streptomycin, Gibco, 15140-122) at 37C with 5% CO 2