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Gut microbe-generated metabolite trimethylamine N-oxide and the risk of diabetes: a systematic review and dose-response meta-analysis

239 (1), 7076 (1996) R
PLoS ONE 9 , e97330 (2014)

Horizontal pleiotropy occurs when the instrumental variables affect the outcome through mechanisms other than the exposure of interest, which may distort the causal effect estimation

Li HG, et al
