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p = 0.1106) on measured level of GSSG (Fig

[PubMed] [Google Scholar] 9.Srivastava SK, Beutler E

For example, athletes with high metabolic demands, vegans who consume no dietary B12, or individuals with chronic malabsorption issues like Crohns disease may find they feel their best with a bi-weekly (every two weeks) injection
However, the effect of C677T polymorphisms of MTHFR on cognitive function was not significant in normal subjects as a longitudinal cognitive study showed that the MTHFR C677T polymorphism was not associated with cognitive performance at baseline or over 12 years 49

This may suggest that a different mechanism is at play, which could relate to the abnormal immune response present in ME/CFS (311)