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Oncotarget 8 , 107167107175 (2017)

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Use against tuberculosis continued, as isoniazid's effectiveness against the disease outweighs its risks

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Since Tph and Tfh cells support B cell differentiation and antibody production, their reduction impairs humoral immune responses, further hindering HBV clearance ( 4.4 NK cells NK cells are key innate immune effectors in HBV infection, where they control viral replication through cytolysis, degranulation, and secretion of antiviral cytokines such as IFN- and TNF- ( Alcohol exposure further disrupts NK cell function in HBV-infected livers