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Children aged 412 years were diagnosed with ASD according to DSM criteria, both boys and girls were included, and the study explicitly excluded participants with major psychiatric comorbidities such as ADHD, depressions, bipolar disorder, anxiety disorders, epilepsy, severe intellectual disabilities, or recent antipsychotic use, ensuring relative homogeneous sample focused on irritability

Ren, J., Ding, X

Adenosylmethionine decarboxylase 1 activity is regulated by product inhibition and allosterically stimulated by putrescine

Fast synaptic action by glutamate is mediated via ionotropic receptors, which include a heterogenous family of tetrameric ligand-gated channels classified based on their structural homology and response to pharmacological agonists