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doi: 10.1002/2211-5463.13504 54 ByunS-ESimCChungYKimHKParkSKimDKet al

Salinas-Snchez et al., 2011

Marginal maternal zinc deficiency produces liver damage and altered zinc transporter expression in offspring male rats
Prevention of breast cancer growth, invasion, and metastasis by antiestrogen tamoxifen alone or in combination with urokinase inhibitor B-428

If an ingredient is fragile, like glutathione, it needs a "security detail" to get it through the harsh environment of the stomach and the hostile enzymes of the small intestine