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Description
IR promotes hepatic steatosis and increases ROS levels by causing hyperglycemia and hyperinsulinemia due to reduced mitochondrial beta-oxidation

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The influence doxorubicin has on GSH depletion is most certainly also dependent upon the cell-type and tissue-type in question
doi: 10.1016/S0022-2143(97)90096-2

Pain levels may remain unchanged or show minor improvement
