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Thats exactly what your tri-modality method is designed to do
Prescribing an unapproved new drug outside a trial is technically illegal under the FDCA (aside from narrow compassionate-use exceptions)

The early human evidence is suggestive

Protocols describe a fresh syringe every time they cost pennies

10.1080/19490976.2015.1134082 Gut Microbes 133 MullerP