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To exert its protective effects, AMPK signaling interacts with other molecular pathways, including PGC-1, PI3K/Akt, NOX4, and NF-B ( Sirt1 is another key regulator in the autophagy process, particularly in metabolic diseases such as DKD (Kitada et al., 2017
2012;7 doi: 10.1371/journal.pone.0030543

Differences between acylcarnitine profiles in plasma and bloodspots
