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Assuming that the mutational flexibility of these residues was similar in the proto-ribosome, the pore at the PTC that would eventually evolve into the exit tunnel was likely formed from residues of varying mutational flexibility

Neural Regener Res (2018) 13(5):896907

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[2] However, monodehydroascorbate is a radical and if not rapidly reduced it disproportionates into ascorbate and dehydroascorbate (DHA)