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Ro 25-6981 and CP-101,606 also cross-discriminate with phencyclidine in drug discrimination paradigms in rats [158, 159] and primates [159] and CP-101,606 is self-administered by primates experienced in self-administration of phencyclidine [159], indicating that some GluN2B NAMs share discriminative stimulus properties with the channel blocker phencyclidine