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Extracellular NAD + can enter cells via pore-forming channel connexin 43 (Cx43), a bi-directional NAD + transporter allowing exogenous NAD + transportation into the cell, and transportation out for utilization of NAD + by CD38 64

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Front Plant Sci 3(4):400415 Vance E (2021) Metabolic exchanges in symbiosis

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Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers