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Non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin inhibit cyclooxygenase and eventually prostaglandin synthesis

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Smith JW, Matchado AJ, Wu LS-F et al (2022) Longitudinal assessment of prenatal, perinatal, and early-life aflatoxin B1 exposure in 828 motherchild dyads from Bangladesh and Malawi

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Zinc deficiency exacerbates these processes by upregulating molecules like vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), facilitating monocyte attachment and intensifying vascular inflammation and AS progression [475, 476]