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Micron-scale delivery systems like microneedles and microparticles face challenges in intranasal brain targeting, including the limited nasal cavity volume restricting administration volume and the need for precise dosing to reach the olfactory region without causing irritation

The doxorubicin cardiotoxicity studies are particularly noteworthy because this chemotherapy drug causes a type of heart damage that closely resembles natural cardiomyopathy

24 Epitalon is a 4-amino acid pluripotent peptide and regulator of the brain, pineal glands, and retina

Reddy and Raghavendra, 2006)

The association of cannabis use and cardiac dysrhythmias: a systematic review
