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In a seminal study, researchers added Epithalon to human fetal fibroblasts that lacked detectable telomerase activity
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J Eur Acad Dermatol Venereol (2017) 31:20512
TNF- and IL-1 are key inflammatory mediators of IDD, positively correlating with the severity and promoting ECMs catabolism by up-regulating proteolytic enzymes, whilst inhibiting the expression and synthesis of proteoglycan (Le Maitre et al., 2005
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