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For most people, it starts with the typical anemia symptoms - fatigue, pale skin, shortness of breath, etc, and progresses to more neurological symptoms as the condition worsens

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SIRT1 is part of a family of proteins called sirtuins, known as longevity genes. It uses NAD+ as a fuel source to repair DNA, reduce inflammation, and improve stress resistance

EGR-1 is a gene that is considered to respond immediately and is potentially involved in the generation of cytokines and growth factors, as well as the early formation of extracellular matrix components like collagen

Major health organizations do not recommend B12 for weight loss in healthy individuals