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Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition

doi: 10.1189/jlb.1206738

Within 72 hours after injection of 500 to 1000 mcg of hydroxocobalamin, 16 to 66 percent of the injected dose may appear in the urine

In yeast, constitutively active Hsf1 enhances survival under ER stress in both wild-type and UPR-deficient ire1 mutants through multiple pathways, including the induction of KAR2 (Karyogamy 2) the yeast ortholog of hsp-4 15,16,17