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Studies using primary rat ovarian cultures have shown that AMH antagonizes the stimulatory effects of multiple follicular growth factors, including FGF, KITL, and KGF, while downregulating genes associated with the TGF-, MAPK, and FGF signaling pathways 148

ISR, integrated stress response

A series of cross-sectional cohort studies conducted since 2020 in Europe, North America, and Asia have consistently found reduced microbial diversity and altered gut microbial structure in patients with FM (119)

Furthermore, taking them together may enhance their individual effects due to a synergistic relationship