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On the same line, recent studies have reported innovative evidence on the toxicological effects of dietary protein carbonyls and other oxidized amino acids (Estvez and Xiong 2019) and the role of these compounds in cell signalling mechanisms (Wong et al

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In the nucleus, p53 protein induced autophagy and promoted cell death, while in the cytoplasm p53 inhibited autophagy, which could promote the survival of cancer cells in the occurrence and development of tumors [167]

Bonorris, G

DCA inhibits alanine formation (from pyruvate) through activating pyruvate oxidation to form acetyl CoA to start Krebs cycle and other metabolic pathways